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ea0020p545 | Neuroendocrinology, Pituitary and Behaviour | ECE2009

Pre-treatment IGF-I concentrations predict radiographic osteoarthritis in acromegalic patients with long-term cured disease

Biermasz Nienke R , Wassenaar Moniek J E , van der Klaauw Agatha A , Pereira Alberto M , Smit Johannes W A , Roelfsema Ferdinand , Wolterbeek Ron , Kroon Herman M , Kloppenburg Margreet , Romijn Johannes A

Objective: To identify factors influencing the development of osteoarthritis during long-term control of acromegaly, focusing on disease specific parameters, growth hormone (GH) and insulin-like growth factor I (IGF-I) concentrations and duration of disease, adjusted for the well-known determinants of primary osteoarthritis.Design: Follow-up study.Methods: We studied 67 patients, with adequate biochemical control of acromegaly for ...

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Pre-treatment IGF-I concentrations predict radiographic osteoarthritis in acromegalic patients with long-term cured disease

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